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Open Access Review Issue
SARS-CoV-2: Literature Review Focusing on Structure, Diagnosis and Vaccine Development
Nano Biomedicine and Engineering 2022, 14(4): 343-348
Published: 31 December 2022
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SARS-CoV-2 is a highly pathogenic novel ongoing-pandemic virus. It causes COVID-19. Little is known about SARS-CoV-2 biology, countermeasure, and its origin. SARS-CoV-2 is characterized by high infectiousness and sever pathogenesis. COVID-19 crosses the bounders of all continents in a high spreading manner. Here, several aspects regarding the origin and the molecular structure of this novel virus as well as the production of effective vaccines have been addressed. This article illustrated that SARS-CoV-2 was not being recombined inside laboratory and it has a complicated genome that led to sophisticated pathogenesis. Additionally, an important structural protein known as spike S was demonstrated by researchers as an important protein used by the virus for host cell entry as well as for vaccine development. However, the efforts for viral diagnosis and genomic demonstration as well as vaccine production are promising to tackle COVID-19. These perspectives will help in COVID-19 control. However, further investigations are urgently needed to figure out which controlling tactic is more efficient not only in the case of SARS-CoV-2 but also for future pandemics.

Open Access Research Article Issue
Electrochemical Analysis Using Nano-Sensor of Stevia Herb as a Healthful Alternative Sugar
Nano Biomedicine and Engineering 2021, 13(2): 207-211
Published: 02 June 2021
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Stevia rebaudiana is a plant herb which has good properties for using as an alternative of the glucose sugar. Electrochemical study was used to calculate the limited safety dose by a cyclic voltammetric technique using nano-sensor as modified glassy carbon electrode (GCE) with carbon nanotubes (CNT) as MWCNT/GCE. The oxidation current peak of stevia compound was appeared in the concentration of 0.4 mM (28 mg/mL), and the reduction current peak appeared at –500 mV, and so it can be concluded that stevia compound is an anti-oxidative sweetener compound at a limited concentration for safety using. Also, the electrochemical properties of the stevia compound were studied in acidic and alkaline pH to accord the oxidative behavior in acidic medium and act as anti-oxidative in alkaline solution.

Open Access Research Article Issue
Redox Process of Cardamom Oil in Human Blood Serum Using Cyclic Voltammetry
Nano Biomedicine and Engineering 2020, 12(1): 99-103
Published: 17 March 2020
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Cardamom oil is one of the active herbs used as a treatment in different diseases by the function of the blood serum components. Among the methods used for identification of function group which acted in the human body, the method of electrochemical analysis using cyclic voltammetry was used to determine the effectiveness of cardamom by the oxidation-reduction reaction in the blood medium. Results showed that the cardamom compound presented peaks of oxidation-reduction in the blood serum medium of 0.8 and -0.65 V, respectively. The oxidation peak disappeared in alkaline pH; hence, the cardamom acted as anti-oxidative compound in alkaline medium and with ascorbic acid. But the oxidation peak was enhanced in acidic pH. Other electrochemical parameters of cardamom in blood serum medium were determined, including studies on different scan rates, reliability and stability.

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