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Research Article | Open Access

New Voltammetric Study of MgCl2 as Alternative Contrast Media in MRI Molecular Imaging

Muhammed Mizher Radhi1( ), Haydar Abdulkadeer Taheer Al-Shimmari1, Emad Abbas Jaffar Al-Mulla2( ), Ali Abdulabbas Abdullah3, Ahmed Ghanim Wadday3
Department of Radiological Techniques, Health and Medical Technology College, Middle Technical University, Baghdad, Iraq
College of Health and Medical Techniques, Al-Furat Al-Awsat Technical University, 54003 Al-Kufa, Iraq
College of Engineering Technical, Al-Furat Al-Awsat Technical University, 54001 An-Najaf, Iraq
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Abstract

Gadolinium compounds have been used as a common contrast media in MRI technique; however, they have oxidation-reduction current peaks in blood medium. To propose a solution for this problem, the alternative of contrast media in magnetic resonance imaging (MRI) was studied by electrochemical method using cyclic voltammetric technique. Magnesium compound was chosen such as MgCl2 which has a good electrochemical properties especially in blood medium. It was found that Mg (Ⅱ) ions in blood medium acted as an antioxidative reagent. The results of this study focused on the effect of magnesium chloride ions in normal saline, KCl solution and blood medium in presence with ascorbic acid (AA) and folic acid (FA) and understanding the redox current peaks of Mg (Ⅱ) ions in these conditions. We obtained good results by using MgCl2 solution as an alternative contrast medium in MRI technique instead of using of gadolinium compounds.

Keywords

MRI contrast mediaCyclic voltammetry (CV)MgCl2Ascorbic acid (AA)Folic acid (FA)

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Nano Biomedicine and Engineering
Volume 9 Issue 2,
June 2017
Pages 152-161
DOI: 10.5101/nbe.v9i2.p152-161
Cite this article:
Radhi MM, Al-Shimmari HAT, Al-Mulla EAJ, et al. New Voltammetric Study of MgCl2 as Alternative Contrast Media in MRI Molecular Imaging. Nano Biomedicine and Engineering, 2017, 9(2): 152-161. https://doi.org/10.5101/nbe.v9i2.p152-161

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Received: 29 April 2017
Accepted: 26 June 2017
Published: 30 June 2017
© 2017 Muhammed Mizher Radhi, Haydar Abdulkadeer Taheer Al-Shimmari, Emad Abbas Jaffar Al-Mulla, Ali Abdulabbas Abdullah, and Ahmed Ghanim Wadday.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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