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Research Article | Open Access

Use of Nano-Sensors of the Interferences between Pb((II) with Each of Mg(II), Zn(II), Mn(II), Ca(II), Co(II) and PO4-3 in Blood Medium: An Electrochemical Study

Yousif Kadhim Abdul-Amir1, Muhammed Mizher Radhi2, Emad Abbas Jaffar Al-Mulla3( )
Department of Chemistry, College of Science, Al-Mustanssiria University, Baghdad, Iraq
Department of Radiological Techniques, Health and Medical Technology College-Baghdad, Middle Technical University (MTU), Iraq
College of Health and Medical Techniques, Al-Furat Al-Awsat Technical University, 54003 Al-Kufa, Iraq
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Abstract

Lead is considered a key element in causing autism disease in children due to the pollution of this dangerous element to human. The aim of this research is to obtain a chemical compound with the effect of inhibiting the oxidation of lead ions on the brain that causes the autism disease. Cyclic voltammetric technique was used to study the effect of interferences between lead ions with selected elements such as Mn(II), Mg(II), Zn(II), Ca(II), PO4-3 and Co(II) in blood medium. Multi wall carbon nano tube (MWCNT) which was modified with glassy carbon electrode (GCE) was used as a working electrode sensor in cyclic voltammetric method. The results showed that the oxidation and reduction current peaks of Pb(II) ions in the blood medium appeared at -0.2 and -0.8 V respectively. It was found that Co(II) ions had a significant effect on the Pb(II) ions in blood medium as anti-oxidative reagent by reducing the anodic current peak of Pb(II) with five folds and enhancing the cathodic current peak. But other ions such as Mn(II), Mg(II), Zn(II), Ca(II) and PO4-3 reduced both redox current peaks of Pb(II) in blood medium. It means that Co(II) ions acted as a good anti-oxidative reagent in blood medium which reduced the effect of lead ions on brain cells by the blood stream. Hence, cobalt compounds could be used as drugs for treatment of the autism disease in children.

Keywords

Cyclic voltammetryAutismBlood mediumNano-sensorPb(II)Co(II)

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Nano Biomedicine and Engineering
Volume 9 Issue 3,
September 2017
Pages 199-207
DOI: 10.5101/nbe.v9i3.p199-207
Cite this article:
Abdul-Amir YK, Radhi MM, Al-Mulla EAJ. Use of Nano-Sensors of the Interferences between Pb((II) with Each of Mg(II), Zn(II), Mn(II), Ca(II), Co(II) and PO4-3 in Blood Medium: An Electrochemical Study. Nano Biomedicine and Engineering, 2017, 9(3): 199-207. https://doi.org/10.5101/nbe.v9i3.p199-207

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Received: 07 July 2017
Accepted: 05 September 2017
Published: 12 September 2017
© 2017 Yousif Kadhim Abdul-Amir, Muhammed Mizher Radhi, and Emad Abbas Jaffar Al-Mulla.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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