First, a three-tier coordinated scheduling system consisting of a distribution network dispatch layer, a microgrid centralized control layer, and local control layer in the energy internet is proposed. The multi-time scale optimal scheduling of the microgrid based on Model Predictive Control (MPC) is then studied, and the optimized genetic algorithm and the microgrid multi-time rolling optimization strategy are used to optimize the datahead scheduling phase and the intra-day optimization phase. Next, based on the three-tier coordinated scheduling architecture, the operation loss model of the distribution network is solved using the improved branch current forward-generation method and the genetic algorithm. The optimal scheduling of the distribution network layer is then completed. Finally, the simulation examples are used to compare and verify the validity of the method.