Mining potential and valuable medical knowledge from massive medical data to support clinical decision-making has become an important research field. Personalized medicine recommendation is an important research direction in this field, aiming to recommend the most suitable medicines for each patient according to the health status of the patient. Personalized medicine recommendation can assist clinicians to make clinical decisions and avoid the occurrence of medical abnormalities, so it has been widely concerned by many researchers. Based on this, this paper makes a comprehensive review of personalized medicine recommendation. Specifically, we first make clear the definition of personalized medicine recommendation problem; then, starting from the key theories and technologies, the personalized medicine recommendation algorithms proposed in recent years are systematically classified (medicine recommendation based on multi-disease, medicine recommendation with combination pattern, medicine recommendation with additional knowledge, and medicine recommendation based on feedback) and in-depth analyzed; and this paper also introduces how to evaluate personalized medicine recommendation algorithms and some common evaluation indicators; finally, the challenges of personalized medicine recommendation problem are put forward, and the future research direction and development trends are prospected.

With the developing demands of massive-data services, the applications that rely on big geographic data play crucial roles in academic and industrial communities. Unmanned aerial vehicles (UAVs), combining with terrestrial wireless sensor networks (WSN), can provide sustainable solutions for data harvesting. The rising demands for efficient data collection in a larger open area have been posed in the literature, which requires efficient UAV trajectory planning with lower energy consumption methods. Currently, there are amounts of inextricable solutions of UAV planning for a larger open area, and one of the most practical techniques in previous studies is deep reinforcement learning (DRL). However, the overestimated problem in limited-experience DRL quickly throws the UAV path planning process into a locally optimized condition. Moreover, using the central nodes of the sub-WSNs as the sink nodes or navigation points for UAVs to visit may lead to extra collection costs. This paper develops a data-driven DRL-based game framework with two partners to fulfill the above demands. A cluster head processor (CHP) is employed to determine the sink nodes, and a navigation order processor (NOP) is established to plan the path. CHP and NOP receive information from each other and provide optimized solutions after the Nash equilibrium. The numerical results show that the proposed game framework could offer UAVs low-cost data collection trajectories, which can save at least 17.58% of energy consumption compared with the baseline methods.

In recent years, neural networks have been widely used in natural language processing, especially in sentence similarity modeling. Most of the previous studies focused on the current sentence, ignoring the commonsense knowledge related to the current sentence in the task of sentence similarity modeling. Commonsense knowledge can be remarkably useful for understanding the semantics of sentences. CK-Encoder, which can effectively acquire commonsense knowledge to improve the performance of sentence similarity modeling, is proposed in this paper. Specifically, the model first generates a commonsense knowledge graph of the input sentence and calculates this graph by using the graph convolution network. In addition, CKER, a framework combining CK-Encoder and sentence encoder, is introduced. Experiments on two sentence similarity tasks have demonstrated that CK-Encoder can effectively acquire commonsense knowledge to improve the capability of a model to understand sentences.

Healthcare insurance fraud has caused billions of dollars in losses in public healthcare funds around the world. In particular, healthcare insurance fraud in chronic diseases is especially rampant. Understanding disease progression can help investigators detect healthcare insurance frauds early on. Existing disease progression methods often ignore complex relations, such as the time-gap and pattern of disease occurrence. They also do not take into account the different medication stages of the same chronic disease, which is of great help when conducting healthcare insurance fraud detection and reducing healthcare costs. In this paper, we propose a heterogeneous network-based chronic disease progression mining method to improve the current understanding on the progression of chronic diseases, including orphan diseases. The method also considers the different medication stages of the same chronic disease. Extensive experiments show that our method can outperform the existing methods by 20% in terms of F-measure.