Motor coordination is crucial for preschoolers’ development and is a key factor in assessing childhood development. Current diagnostic methods often rely on subjective manual assessments. This paper presents a machine vision-based approach aimed at improving the objectivity and adaptability of assessments. The method proposed involves the extraction of key points from the human skeleton through the utilization of a lightweight pose estimation network, thereby transforming video assessments into evaluations of keypoint sequences. The study uses different methods to handle static and dynamic actions, including regularization and Dynamic Time Warping (DTW) for spatial alignment and temporal discrepancies. A penalty-adjusted single-frame pose similarity method is used to evaluate actions. The lightweight pose estimation model reduces parameters by 85%, uses only 6.6% of the original computational load, and has an average detection missing rate of less than 1%. The average error for static actions is 0.071 with a correlation coefficient of 0.766, and for dynamic actions it is 0.145 with a correlation coefficient of 0.653. These results confirm the proposed method’s effectiveness, which includes customized visual components like motion waveform graphs to improve accuracy in pediatric healthcare diagnoses.

Alzheimer’s disease (AD) is an irreversible and neurodegenerative disease that slowly impairs memory and neurocognitive function, but the etiology of AD is still unclear. With the explosive growth of electronic health data, the application of artificial intelligence (AI) in the healthcare setting provides excellent potential for exploring etiology and personalized treatment approaches, and improving the disease’s diagnostic and prognostic outcome. This paper first briefly introduces AI technologies and applications in medicine, and then presents a comprehensive review of AI in AD. In simple, it includes etiology discovery based on genetic data, computer-aided diagnosis (CAD), computer-aided prognosis (CAP) of AD using multi-modality data (genetic, neuroimaging and linguistic data), and pharmacological or non-pharmacological approaches for treating AD. Later, some popular publicly available AD datasets are introduced, which are important for advancing AI technologies in AD analysis. Finally, core research challenges and future research directions are discussed.

The current mode of clinical aided diagnosis of Ocular Myasthenia Gravis (OMG) is time-consuming and laborious, and it lacks quantitative standards. An aided diagnostic system for OMG is proposed to solve this problem. The values calculated by the system include three clinical indicators: eyelid distance, sclera distance, and palpebra superior fatigability test time. For the first two indicators, the semantic segmentation method was used to extract the pathological features of the patient’s eye image and a semantic segmentation model was constructed. The patient eye image was divided into three regions: iris, sclera, and background. The indicators were calculated based on the position of the pixels in the segmentation mask. For the last indicator, a calculation method based on the Eyelid Aspect Ratio (EAR) is proposed; this method can better reflect the change of eyelid distance over time. The system was evaluated based on the collected patient data. The results show that the segmentation model achieves a mean Intersection-Over-Union (mIoU) value of 86.05%. The paired-sample T-test was used to compare the results obtained by the system and doctors, and the $p$ values were all greater than 0.05. Thus, the system can reduce the cost of clinical diagnosis and has high application value.