The construction of silicon–oxygen bonds has been highlighted as an exciting achievement in organosilicon and green chemistry, but their synthetic efficiency has great improvement potential, so it is crucial to explore and achieve an effective approach for synthesizing such compounds. In this study, we successfully prepared the highly dispersed platinum single-atom catalyst (Pt SAC/N-C) through a coordination-assisted strategy with a mixture of ligands (H₂bpdc and H₂bpydc), which were used for the O-silylation of alcohols with silanes. The strong coordination between Pt²⁺ and the Pyridine N at the skeleton of UiO-67 plays a critical role in accessing the atomically isolated dispersion of Pt sites. Without the assistance of the H₂bpydc ligands, the Pt/ UiO-67-bpdc precursor is prone to aggregation during the pyrolysis process, resulting in the formation of Pt nanoparticles. Aided by advanced characterization techniques of high-angle annular dark-field scanning transmission electron microscopy (HAADF-STEM) and X-ray absorption fine structure (XAFS) spectroscopy, it has been demonstrated that atomically dispersed Pt was formed on the UiO-67 through a local structure of four-coordinated Pt-N₄, exhibiting a high actual Pt loading content (0.6962 wt.%). In the oxidation of silanes, the Pt SAC/N-C catalyst showed a high turnover frequency (TOF) value (up to 9,920 h⁻¹) when the catalyst loading decreased to 0.005%. Excellent performance was maintained during recycling experiments, indicating high stability of the catalyst.

Originated from nature and used for nature is a way of sustainable development. In this work, montmorillonite (MMT), a natural two-dimensional (2D) layered mineral, the surface and interlayer of which were nano-decorated by chemical synthesis technique was applied in biological detection field. Magnetic ferrite (Co_0.5Ni_0.5Fe₂O₄) was anchored on the surface and intercalated in the interlayer of montmorillonite, which served as a competitive candidate of enzyme mimics. Cytotoxicity test toward HUVEC and Hela cells verified the good biocompatibility of Co_0.5Ni_0.5Fe₂O₄-MMT, guaranteeing its safety in biological applications. Based on the peroxidase-like activity of Co_0.5Ni_0.5Fe₂O₄-MMT, a colorimetric sensing platform for H₂O₂ was established by a facile mix-and-detect approach with the detection limit of 0.565 μM (3σ/slope). It was implied that the peroxidase-like activity of Co_0.5Ni_0.5Fe₂O₄-MMT was originated from generation of ·OH and ·O₂^– produced from catalytic decomposition process of H₂O₂. Coupled with cascaded catalytic reactions of ACh, a facile and efficient sensing platform for ACh with satisfactory anti-interference ability was established. Thus, all these remarkable features highlighted the superiority of Co_0.5Ni_0.5Fe₂O₄-MMT, and endowed it with a powerful competitiveness in the fields of environmental assessing, biosensing, and disease monitoring.