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Open Access Review Article Issue
Nutraceutical support for respiratory diseases
Food Science and Human Wellness 2018, 7 (3): 205-208
Published: 05 September 2018
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Respiratory diseases have been a major health concern for human beings since several decades. Soothing the irritated nasal passages and airways had been a mutual necessity in multiple ancient cultures. In ancient China, herbs were largely used to help deal with cough and reduce mucus, thereby maintaining respiratory health. In India, knowledge of herb-related remedies passed down through generations. In the human society, freshly prepared herb ointments, including air-dried herbs, and boiled herbal soups have had a long history of combining botanical nutrients with local cuisine.

Although the use of herbs and natural products from plants (NPFPs) has been primarily cited in reviews based on modern respiratory diseases, the concept of soothing and alleviating disease progression or reducing mucus production has been highly valued. Nevertheless, only a few herbs could directly disrupt the irreversible fibrotic progression. On the other hand, natural products from animals (NPFAs) have more potential in disrupting procollagen or extracellular matrix deposition. Due to these reasons, NPFAs could be considered as important functional foods for patients with respiratory diseases. In this article, we provide a review of both NPFAs and NPFPs that are adjuvant to respiratory health.

Open Access Research Article Issue
Anticancer effect of curcumin on breast cancer and stem cells
Food Science and Human Wellness 2018, 7 (2): 134-137
Published: 09 June 2018
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Numerous studies have shown that curcumin, a natural compound, exerts anticancer effects by inhibiting cancer cell proliferation and metastasis and by inducing cell cycle arrest and apoptosis. In particular, curcumin exhibits potent inhibitory effects on breast cancer, the most prevalent type of cancer among women worldwide. It has low maximal inhibitory concentration for breast cancer cell lines that express the hormone receptor ER and sensitizes cell lines to anticancer drugs. Moreover, it can induce apoptosis in cell lines independently of hormone receptor expression. In addition, curcumin inhibits the proliferation of breast cancer stem cells (BCSC), an important factor that influences cancer recurrence. The inhibition of BCSC proliferation suppresses metastasis and reattachment, ultimately limiting tumor formation. A xenograft study similarly showed that curcumin exerts tumor-suppression effects on cancer cells and cancer stem cells. Therefore, curcumin is a potential anticancer compound, and its concurrent application with other anticancer drugs appears promising.

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