Identification of water potential areas in arid regions is a crucial element for the enhancement of their water resources and socio-economic development. In fact, water resources system-planning can be used to make various decisions and implement management of water resources policies. The purpose of this study is to identify groundwater storage areas in the high Guir Basin by implementing Geographic Information System (GIS) and Remote Sensing methods. The required data for this study can be summarized into five critical factors: Topography (slope), lithology, rainfall, rock fracture and drainage. These critical factors have been converted by the GIS into thematic maps. For each critical parameter, a coefficient with weight was attributed according to its importance. The map of potential groundwater storage areas is obtained by adding the products (coefficient × weight) of the five parameters. The results show that 50% to 64% of the total area of the High Guir Basin is potentially rich in groundwater, where most of fracture systems are intensely developed. The obtained results are validated with specific yield of the aquifer in the study area. It is noted that there is a strong positive correlation between excellent groundwater potential zones with high flows of water points and it diminishes with low specific yield with poor potential zones.