BCube is one kind of important data center networks. Hamiltonicity and Hamiltonian connectivity have significant applications in communication networks. So far, there have been many results concerning fault-tolerant Hamiltonicity and fault-tolerant Hamiltonian connectivity in some data center networks. However, these results only consider faulty edges and faulty servers. In this paper, we study the fault-tolerant Hamiltonicity and the fault-tolerant Hamiltonian connectivity of BCube(n,k) under considering faulty servers, faulty links/edges, and faulty switches. For any integers n ≥ 2 and k ≥ 0, let BC_n,k be the logic structure of BCube(n,k) and F be the union of faulty elements of BC_n,k. Let f_v, f_e, and f_s be the number of faulty servers, faulty edges, and faulty switches of BCube(n,k), respectively. We show that BC_n,k − F is fault-tolerant Hamiltonian if f_v +f_e + (n − 1)f_s ≤ (n − 1)(k + 1) − 2 and BC_n,k −F is fault-tolerant Hamiltonian-connected if f_v + f_e + (n − 1)f_s ≤ (n − 1)(k + 1) − 3. To the best of our knowledge, this paper is the first work which takes faulty switches into account to study the fault-tolerant Hamiltonicity and the fault-tolerant Hamiltonian connectivity in data center networks.