With the aim of preventing iatrogenic shot trunk, stiffness and rotation deformity caused by long-term fixation with usual locked pedicle screw system, a new kind of slidable pedicle screw frame system was designed and fabricated to treat patients with spinal deformity in the growth period. The frame was composed of slidable and locked pedicle screws, cross-links and double rods. The middle part of double rods was fixed with locked pedicle screws and two ends of them were with slidable ones. The spine longitudinal and transverse growth was not limited. 360 patients including 82 congenital scoliosis, 110 idiopathic scoliosis, 60 kyphosis, 44 spinal fractures and 63 spinal tumors or tuberculosis were treated. The average preoperative Cobb’s angle of scoliosis was 66.43°, post-operative one was 22.43°and lost 5° with average 14 months of following-up (6-37 months). The total longitudinal growth of adolescent spinal deformity was 86.4 cm (mean 0.9 cm). In conclusion, slidable pedicle screw frame system is successfully designed and fabricated, also stable and effective to correct the spinal deformities in adolescent growth period. The longitudinal and transverse spine growth of post-operation patients was not limited, and no complications such as stiffness, vertebrae rotation and crank shaft happened for post-operation patients.