The average temperature of Thailand is projected to increase by 2-3 ℃, and the annual rainfall is projected to increase by 25% and up to 50% in certain areas. The climate change in future is expected to provide changes in hydrological cycle and therefore impacts the groundwater resources too. In this study, we analyzed the general climate change trends and reviewed the groundwater conditions of Thailand. The climate changes, hydrologic variability and the impact of climate change on groundwater sustainability are also discussed based on a national groundwater monitoring program. Currently, there are 864 groundwater monitoring stations and 1524 monitoring wells installed in Thailand. Moreover, the impact of climate change on groundwater-dependent systems and sectors is also discussed according to certain case studies, such as saline water intrusion in coastal and inland areas. Managing aquifer recharge and other projects are examples of groundwater adaptation project for the future.