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Biogenic Synthesis of Copper Oxide Nanoparticles Using Falcaria vulgaris L. Leaf Extract and Assessment of Its Antibacterial Activity against Salmonella Paratyphi-A
Nano Biomedicine and Engineering
Published: 04 July 2024
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The copper oxide nanoparticle has attracted increasing attention among all metal oxides due to its distinctive properties and applications. Chemical and physical methods of synthesizing copper oxide nanoparticles are challenged by high reagent costs, equipment limitations, and environmental hazards. Following green chemistry principles, copper oxide nanoparticles were synthesized using Falcaria vulgaris leaf extract as a bio-reducing agent and copper nitrate as a source of copper in this study. As a result, copper oxide nanoparticles can be produced without the use of organic chemicals, and this method is non-toxic, economically viable, easily scaled up, and takes less time to produce. The formation of copper oxide nanoparticles was confirmed by the dominant surface plasmon resonance (SPR) peak at 350 nm. Based on scanning electron microscope (SEM) images, the particles were spherical and morphologically sized between 58–200 nm. Energy dispersive X-ray spectroscopy (EDX) analysis confirmed the presence of Cu and O in the pyhto-synthesized nanoparticles. Fourier transform infrared (FTIR) spectroscopy as well showed a distinct peak of Cu–O stretching vibration positioned at 609.36 cm–1. The structural characterization was performed utilizing X-ray diffraction (XRD) in line with reflections of the face-centered cubic (fcc) phase of the copper oxide nanoparticles. The average particle size of nanoparticles was found to be 82.9 nm by using XRD analysis and Scherrer equation. In addition, since Salmonella Paratyphi-A is less studied than many other bacteria, we examined the antibacterial properties of copper oxide nanoparticles, against this relatively resistant bacterium. By checking the inhibition zone and minimum concentration of phyto-synthesized nanoparticles, it was determined that they effectively inhibited bacteria growth.

Open Access Research Article Issue
Biosynthesis of Zinc Oxide Nanoparticles Using Punica granatum L. Waste Peel Extract, and Assessment of Antioxidant and Catalytic Activity
Nano Biomedicine and Engineering 2023, 15(4): 378-388
Published: 08 September 2023
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Downloads:275

Green synthesis assisted by plant extracts is a recent research focus in diverse branches of chemistry. Through simple synthesis, different nanoparticles (NPs) can be produced that include oxides of zinc, copper, magnesium, or silver using various types of plant extracts. A remarkable attribute of plant aqueous extracts is their capability to act as reducing and capping agents. This study assessed the antioxidant and catalytic properties of phytosynthesized zinc oxide (ZnO) NPs using the fresh aqueous extract of pomegranate (Punica granatum) peel. Scanning electron microscopy indicated that the produced NPs had an average size of 49.52 nm with a spherical shape. X-ray diffraction confirmed the hexagonal phase of ZnO NPs and that their average crystallite size was 41.23 nm according to the Scherrer equation. Analysis of the ultraviolet–visible spectrum was performed to confirm the formation of ZnO NPs, and Fourier transform-infrared analysis illustrated the presence of diverse phytochemicals in the plant extract and ZnO NPs. The 2,2-diphenyl-1-picrylhydrazyl assay was used to determine the radical scavenging activity of these NPs. The novel ZnO phyto-nanocatalyst mediated by extracts from plant waste material, exhibited a well-defined reduction of methylene blue dye. Within 20 min, the catalytic degradation of methylene blue was completed, demonstrating that ZnO NPs have excellent catalytic properties.

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