A comprehensive modeling strategy for studying the thermomechanical tribological behaviors is proposed in this work. The wear degradation considering the influence of temperature (T) is predicted by Archard wear model with the help of the UMESHMOTION subroutine and arbitrary Lagrangian–Eulerian (ALE) remeshing technique. Adopting the proposed method, the thermomechanical tribological behaviors of railway vehicle disc brake system composed of forged steel brake disc and Cu-based powder metallurgy (PM) friction block are studied systematically. The effectiveness of the proposed methodology is validated by experimental test on a self-designed scaled brake test bench from the perspectives of interface temperature, wear degradation, friction noise and vibration, and contact status evolution. This work can provide an effective way for the investigation of thermomechanical tribological behaviors in the engineering field.