In this paper, a hardware-in-the-loop simulation platform for distribution system is developed based on real-time digital simulation system (RTDS) and programmable logic controller (PLC). The hardware in the platform consists of NovaCor simulator, I/O, PLC, HMI, and PC. The NovaCor simulator can realize the simulation of the operation status of the distribution network in real time, and its data interaction is realized by I/O. The structure and loads of the distribution network can be adjusted using the touch screen and PLC, monitoring its real-time operation status. The modular-designed simulation platform can adjust the network and operation parameters according to experimental needs. The modular-designed simulation platform also improves its flexibility and operability by developing corresponding input and output interfaces for real-time information interaction on the platform.