This study established a method using gas chromatography-electrostatic field Orbitrap high-resolution mass spectrometry (Orbitrap GC-MS) for the simultaneous determination of 70 organic pollutants across four categories: organochlorine pesticides (OCPs), polycyclic aromatic hydrocarbons (PAHs), polychlorinated biphenyls (PCBs), and phthalates (PAEs) in infant cereal-based supplementary foods. Techniques integrating cryogenic centrifugation and lipid and protein adsorbent (LPAS) purification were employed. The precise mass numbers of target compounds were determined by Orbitrap GC-MS in full-scan mode (Full MS), which effectively minimized matrix interferences in these foods. Method validation on rice flour samples demonstrated that the 70 compounds exhibited excellent linearity within their respective mass concentration ranges, with correlation coefficients all exceeding 0.995. The detection limits for this method ranged from 0.10-1.0 μg/kg, while the quantification limits varied from 0.3-3.0 μg/kg, meeting the established detection requirements. The average spike recovery of the 70 compounds at three spiked levels (5, 20, and 100 μg/kg) ranged from 75.3%-119.3%, with relative standard deviations ranging from 1.8%-10.8%. Both inter-day and intra-day precision demonstrated relative standard deviation values below 15%. This method was applied to analyze 100 samples of commercial infant cereal-based supplementary food, revealing the presence of PAEs and PAHs in 12.0% of the samples. Notably, no OCPs or PCBs were detected. The detected concentrations of benzo[a]pyrene (BaP) and dibutyl phthalate (DBP) were (4.2 ± 0.1) μg/kg and (1.8 ± 0.3) μg/kg, respectively. This method is straightforward, highly sensitive, and suitable for the rapid screening and confirmation of 70 organic pollutants in infant cereal-based supplementary foods.

As an important part of modern diet, the elemental composition of pre-prepared meat (PM) directly affects consumers’ health. This study aims to reveal the true content and distribution characteristics of elements in PM through inductively coupled plasma-tandem mass spectrometry (ICP-MS/MS), providing a scientific basis for food safety regulation, nutritional assessment and product development. This study optimized the pretreatment conditions, ultimately selecting 5 mL of HNO₃ + 2 mL of 30% H₂O₂ as the digestion reagent, and using microwave digestion conditions with a maximum temperature of 190 °C to digest the samples, and then detecting the content of various elements in PM through ICP-MS/MS. The results showed that all elements had good linear relationships with the linear correlation coefficients greater than 0.999 7. The detection limits ranging from 0.620 to 421 ng/L, the spiked recoveries reach 93.4%–105.0%, and the relative standard deviations less than 5.89%. The measurement results of the national standard chicken meat substance (GBW10018) are all within the standard deviation range of the standard value, which indicates that this method has high accuracy and precision and is suitable for the detection of PM products. Using this method, we evaluated the content of 22 elements in PM, including pork, beef, mutton, chicken and duck meat. The results showed that the contents of Ca, Mg, Zn, and Fe in the five types of PM were relatively high, while the contents of heavy metal elements were very low. This study provides technical support for the strict monitoring of PM, which also offers consumers a more transparent and secure basis for food selection, thereby promoting the popularization of healthy eating concepts.