Artificial Intelligence (AI) is based on algorithms that allow machines to make decisions for humans. This technology enhances the users’ experience in various ways. Several studies have been conducted in the field of education to solve the problem of student orientation and performance using various Machine Learning (ML) algorithms. The main goal of this article is to predict Moroccan students’ performance in the region of Guelmim Oued Noun using an intelligent system based on neural networks, one of the best data mining techniques that provided us with the best results.